DUTASOFT DUTASTERIDE SOFTGELATIN CAPSULES

Dutasteride softgelatin capsules contain the active ingredient dutasteride (0.5 mg), a dual 5-alpha reductase inhibitor that reduces levels of dihydrotestosterone (DHT)—a hormone responsible for prostate growth and hair loss.

Key Uses

1. Benign Prostatic Hyperplasia (BPH)

• Helps shrink an enlarged prostate
• Improves urinary flow
• Reduces risk of acute urinary retention and need for surgery

2. Male Pattern Hair Loss (Off-label)

• Reduces scalp DHT levels
• Helps slow hair thinning and promote regrowth

Mechanism of Action

Dutasteride works by inhibiting Type I and Type II 5-alpha reductase enzymes, which convert testosterone into DHT.

• Can reduce DHT levels by over 90%
• Leads to decreased prostate size and reduced hair follicle miniaturization

Dosage & Administration

• Standard dose: 0.5 mg once daily
• Capsule should be:
  • Swallowed whole (not crushed or chewed)
  • Taken with or without food
• Noticeable results may take 3–6 months

Benefits

• Long half-life (3–5 weeks) allows sustained action
• Effective reduction in prostate volume over time
• Convenient once-daily dosing